Journal article
The Healthy Brain Project: An Online Platform for the Recruitment, Assessment, and Monitoring of Middle-Aged Adults at Risk of Developing Alzheimer's Disease
YY Lim, N Yassi, L Bransby, M Properzi, R Buckley
Journal of Alzheimer S Disease | IOS PRESS | Published : 2019
DOI: 10.3233/JAD-181139
Abstract
Characterizing the earliest demonstrable cognitive decline in middle-aged adults at risk of Alzheimer's disease (AD) will allow for the better understanding of the early disease trajectory, and the provision of therapies prior to clinical symptom onset. We developed an online platform -healthybrainproject.org.au (Healthy Brain Project; HBP) -to recruit, assess, and monitor at-risk middle-aged adults. Objective: Describe the HBP methodology and report baseline characteristics and adherence indices of participants. Methods: Between February 2017 and August 2018, 4,000 community-based middle-aged Australian adults with a first or second-degree family history of dementia enrolled at our website ..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
Funding for the Healthy Brain Project was provided by the National Health and Medical Research Council (GNT1111603, GNT1105576, GNT1104273, GNT1147465) and the Alzheimer's Association (USA) (AARG-17-501424). We would like to thank our study partners (PearlArc, SRC Innovations, Cogstate Ltd, Cambridge Cognition) for their support of the Healthy Brain Project. The Florey Institute of Neuroscience and Mental Health acknowledges support from the Victorian Government, in particular funding from the Operational Infrastructure Support Grant. We thank Paul Maruff for his comments and contributions to an earlier draft of this manuscript. We thank the media team of the Florey Institute of Neuroscience and Mental Health (particularly Amanda Place, Jane Standish and Dr Tom Keeble), the team at KAYO Consulting, Eddie McGuire and the Collingwood Football Club for assisting us with the recruitment of participants. We also thank all those who participated in the study for their commitment and dedication to helping advance research into the early detection and causation of Alzheimer's disease.